L40F (p.Leu40Phe) variant of IL23A (Interleukin-23 subunit alpha)
L40F (p.Leu40Phe) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L40F (p.Leu40Phe) variant details
- p.Leu40Phe
- gnomAD 12-56339162-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.21
- MetaLR 0.11
- MetaSVM -0.91
- CADD 24.30
- PolyPhen-2 0.46
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available