L36P (p.Leu36Pro) variant of IL23A (Interleukin-23 subunit alpha)
L36P (p.Leu36Pro) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
L36P (p.Leu36Pro) variant details
- p.Leu36Pro
- gnomAD 12-56339151-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- REVEL 0.55
- MetaLR 0.32
- MetaSVM -0.38
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available