L36I (p.Leu36Ile) variant of IL23A (Interleukin-23 subunit alpha)
L36I (p.Leu36Ile) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
L36I (p.Leu36Ile) variant details
- p.Leu36Ile
- gnomAD 12-56339150-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.33
- MetaLR 0.33
- MetaSVM -0.34
- CADD 24.60
- PolyPhen-2 0.98
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available