L36F (p.Leu36Phe) variant of IL23A (Interleukin-23 subunit alpha)
L36F (p.Leu36Phe) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L36F (p.Leu36Phe) variant details
- p.Leu36Phe
- gnomAD rs1289222563
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.35
- MetaLR 0.33
- MetaSVM -0.35
- CADD 23.70
- PolyPhen-2 0.99
- SIFT 0.04
- Most common in the East Asian population (allele frequency 5.1e-05)
- Structural context available