L2R (p.Leu2Arg) variant of IL23A (Interleukin-23 subunit alpha)
L2R (p.Leu2Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L2R (p.Leu2Arg) variant details
- p.Leu2Arg
- gnomAD 12-56339049-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.35
- MetaLR 0.08
- MetaSVM -1.01
- CADD 22.90
- PolyPhen-2 0.25
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available