L12M (p.Leu12Met) variant of IL23A (Interleukin-23 subunit alpha)
L12M (p.Leu12Met) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L12M (p.Leu12Met) variant details
- p.Leu12Met
- gnomAD 12-56339078-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.21
- MetaLR 0.26
- MetaSVM -0.61
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available