L11S (p.Leu11Ser) variant of IL23A (Interleukin-23 subunit alpha)
L11S (p.Leu11Ser) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L11S (p.Leu11Ser) variant details
- p.Leu11Ser
- gnomAD 12-56339076-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.09
- MetaLR 0.09
- MetaSVM -0.98
- CADD 22.70
- PolyPhen-2 0.13
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available