L10M (p.Leu10Met) variant of IL23A (Interleukin-23 subunit alpha)
L10M (p.Leu10Met) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- gnomAD 12-56339072-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.16
- MetaLR 0.14
- MetaSVM -0.94
- CADD 23.90
- PolyPhen-2 0.60
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available