G3R (p.Gly3Arg) variant of IL23A (Interleukin-23 subunit alpha)
G3R (p.Gly3Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
G3R (p.Gly3Arg) variant details
- p.Gly3Arg
- gnomAD 12-56339051-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.05
- MetaLR 0.12
- MetaSVM -0.94
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2e-06)
- Structural context available
- Literature evidence available