G25S (p.Gly25Ser) variant of IL23A (Interleukin-23 subunit alpha)
G25S (p.Gly25Ser) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G25S (p.Gly25Ser) variant details
- p.Gly25Ser
- gnomAD 12-56339117-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -0.98
- CADD 8.89
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available