G25D (p.Gly25Asp) variant of IL23A (Interleukin-23 subunit alpha)
G25D (p.Gly25Asp) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- TOPMed rs1876395700
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -0.99
- CADD 11.00
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available