G25C (p.Gly25Cys) variant of IL23A (Interleukin-23 subunit alpha)
G25C (p.Gly25Cys) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G25C (p.Gly25Cys) variant details
- p.Gly25Cys
- gnomAD 12-56339117-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.05
- CADD 15.70
- PolyPhen-2 0.07
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available