G24R (p.Gly24Arg) variant of IL23A (Interleukin-23 subunit alpha)
G24R (p.Gly24Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
G24R (p.Gly24Arg) variant details
- p.Gly24Arg
- TOPMed rs1490875264
- gnomAD rs1490875264
- Missense
- Variant Prioritization Score for Impact Estimate 0.0984
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -0.98
- CADD 8.02
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available