C33R (p.Cys33Arg) variant of IL23A (Interleukin-23 subunit alpha)
C33R (p.Cys33Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
C33R (p.Cys33Arg) variant details
- p.Cys33Arg
- Ensembl rs200361320
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.19
- MetaLR 0.08
- MetaSVM -1.05
- CADD 17.60
- PolyPhen-2 0.40
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available