A6V (p.Ala6Val) variant of IL23A (Interleukin-23 subunit alpha)
A6V (p.Ala6Val) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A6V (p.Ala6Val) variant details
- p.Ala6Val
- TOPMed rs1020985680
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.10
- MetaLR 0.09
- MetaSVM -1.00
- CADD 16.20
- PolyPhen-2 0.43
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available