A21V (p.Ala21Val) variant of IL23A (Interleukin-23 subunit alpha)
A21V (p.Ala21Val) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- gnomAD 12-56339106-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.15
- MetaLR 0.09
- MetaSVM -0.92
- CADD 14.80
- PolyPhen-2 0.02
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available