A21T (p.Ala21Thr) variant of IL23A (Interleukin-23 subunit alpha)
A21T (p.Ala21Thr) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- gnomAD 12-56339105-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.10
- MetaLR 0.08
- MetaSVM -0.98
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available