A17V (p.Ala17Val) variant of IL23A (Interleukin-23 subunit alpha)
A17V (p.Ala17Val) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A17V (p.Ala17Val) variant details
- p.Ala17Val
- TOPMed rs761463787
- gnomAD rs761463787
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.10
- MetaLR 0.08
- MetaSVM -0.99
- CADD 4.95
- PolyPhen-2 0.02
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available