Y49C (p.Tyr49Cys) variant of IL1RN (P18510)
Y49C (p.Tyr49Cys) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
Y49C (p.Tyr49Cys) variant details
- p.Tyr49Cys
- TOPMed rs1687087705
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.34
- MetaLR 0.09
- MetaSVM -1.07
- CADD 27.40
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available