V43G (p.Val43Gly) variant of IL1RN (P18510)
V43G (p.Val43Gly) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V43G (p.Val43Gly) variant details
- p.Val43Gly
- ExAC rs755071562
- TOPMed rs755071562
- gnomAD rs755071562
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.24
- MetaLR 0.04
- MetaSVM -1.11
- CADD 23.00
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available