S28P (p.Ser28Pro) variant of IL1RN (P18510)
S28P (p.Ser28Pro) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
S28P (p.Ser28Pro) variant details
- p.Ser28Pro
- gnomAD 2-113127706-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0832
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.08
- CADD 4.00
- PolyPhen-2 0.03
- SIFT 0.26
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- Literature evidence available