S28A (p.Ser28Ala) variant of IL1RN (P18510)
S28A (p.Ser28Ala) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
S28A (p.Ser28Ala) variant details
- p.Ser28Ala
- gnomAD 2-113127706-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0718
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -1.06
- CADD 0.52
- PolyPhen-2 0.00
- SIFT 0.62
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available