R39K (p.Arg39Lys) variant of IL1RN (P18510)
R39K (p.Arg39Lys) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R39K (p.Arg39Lys) variant details
- p.Arg39Lys
- cosmic curated COSV52080
- Ensembl rs1687014223
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.12
- MetaLR 0.06
- MetaSVM -1.08
- CADD 35.00
- PolyPhen-2 0.48
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available