L7S (p.Leu7Ser) variant of IL1RN (P18510)
L7S (p.Leu7Ser) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
L7S (p.Leu7Ser) variant details
- p.Leu7Ser
- rs1373711868
- gnomAD 2-113118026-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- MetaLR 0.07
- MetaSVM -0.99
- CADD 3.53
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available