L7I (p.Leu7Ile) variant of IL1RN (P18510)
L7I (p.Leu7Ile) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L7I (p.Leu7Ile) variant details
- p.Leu7Ile
- rs1293345956
- gnomAD 2-113118025-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- MetaLR 0.05
- MetaSVM -1.05
- CADD 7.97
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available