L7F (p.Leu7Phe) variant of IL1RN (P18510)
L7F (p.Leu7Phe) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- gnomAD rs1224903381
- Missense
- Variant Prioritization Score for Impact Estimate 0.0495
- REVEL 0.02
- CADD 2.52
- PolyPhen-2 0.05
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available