L55I (p.Leu55Ile) variant of IL1RN (P18510)
L55I (p.Leu55Ile) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L55I (p.Leu55Ile) variant details
- p.Leu55Ile
- gnomAD rs1289272328
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.19
- MetaLR 0.15
- MetaSVM -0.66
- CADD 23.20
- PolyPhen-2 0.56
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available