L50R (p.Leu50Arg) variant of IL1RN (P18510)
L50R (p.Leu50Arg) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L50R (p.Leu50Arg) variant details
- p.Leu50Arg
- gnomAD rs1687087901
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.33
- MetaLR 0.10
- MetaSVM -1.05
- CADD 27.30
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available