L18V (p.Leu18Val) variant of IL1RN (P18510)
L18V (p.Leu18Val) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L18V (p.Leu18Val) variant details
- p.Leu18Val
- ExAC rs752268718
- gnomAD rs752268718
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.15
- CADD 15.40
- PolyPhen-2 0.51
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available