L16V (p.Leu16Val) variant of IL1RN (P18510)
L16V (p.Leu16Val) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- gnomAD 2-113127670-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.07
- CADD 14.40
- PolyPhen-2 0.17
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available