L15F (p.Leu15Phe) variant of IL1RN (P18510)
L15F (p.Leu15Phe) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- gnomAD rs1490908524
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.07
- CADD 10.20
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available