L11V (p.Leu11Val) variant of IL1RN (P18510)
L11V (p.Leu11Val) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L11V (p.Leu11Val) variant details
- p.Leu11Val
- TOPMed rs1275778229
- gnomAD rs1275778229
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.28
- CADD 11.00
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available