L11P (p.Leu11Pro) variant of IL1RN (P18510)
L11P (p.Leu11Pro) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- TOPMed rs1483659610
- gnomAD rs1483659610
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- REVEL 0.43
- CADD 15.20
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available