L11I (p.Leu11Ile) variant of IL1RN (P18510)
L11I (p.Leu11Ile) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L11I (p.Leu11Ile) variant details
- p.Leu11Ile
- TOPMed rs1275778229
- gnomAD rs1275778229
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.26
- CADD 10.80
- PolyPhen-2 0.99
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available