K46N (p.Lys46Asn) variant of IL1RN (P18510)
K46N (p.Lys46Asn) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
K46N (p.Lys46Asn) variant details
- p.Lys46Asn
- gnomAD 2-113129597-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.24
- MetaLR 0.09
- MetaSVM -0.89
- CADD 25.90
- PolyPhen-2 0.82
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available