K34R (p.Lys34Arg) variant of IL1RN (P18510)
K34R (p.Lys34Arg) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
K34R (p.Lys34Arg) variant details
- p.Lys34Arg
- gnomAD 2-113127725-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.02
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available