K31R (p.Lys31Arg) variant of IL1RN (P18510)
K31R (p.Lys31Arg) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K31R (p.Lys31Arg) variant details
- p.Lys31Arg
- TOPMed rs1687013104
- gnomAD rs1687013104
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.06
- MetaLR 0.01
- MetaSVM -0.97
- CADD 12.60
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available