I40F (p.Ile40Phe) variant of IL1RN (P18510)
I40F (p.Ile40Phe) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
I40F (p.Ile40Phe) variant details
- p.Ile40Phe
- gnomAD rs1395406278
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.21
- MetaLR 0.05
- MetaSVM -1.14
- CADD 22.80
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available