I24S (p.Ile24Ser) variant of IL1RN (P18510)
I24S (p.Ile24Ser) in IL1RN (P18510) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
I24S (p.Ile24Ser) variant details
- p.Ile24Ser
- gnomAD 2-113127692-CG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.316
- CADD 12.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available