I24M (p.Ile24Met) variant of IL1RN (P18510)
I24M (p.Ile24Met) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
I24M (p.Ile24Met) variant details
- p.Ile24Met
- ExAC rs778651108
- TOPMed rs778651108
- gnomAD rs778651108
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.05
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available