I24L (p.Ile24Leu) variant of IL1RN (P18510)
I24L (p.Ile24Leu) in IL1RN (P18510) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
I24L (p.Ile24Leu) variant details
- p.Ile24Leu
- gnomAD 2-113127689-AGACG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.62
- CADD 24.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available