H20Y (p.His20Tyr) variant of IL1RN (P18510)
H20Y (p.His20Tyr) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
H20Y (p.His20Tyr) variant details
- p.His20Tyr
- cosmic curated COSV52081
- ExAC rs755803786
- gnomAD rs755803786
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.03
- CADD 10.90
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available