G6S (p.Gly6Ser) variant of IL1RN (P18510)
G6S (p.Gly6Ser) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
G6S (p.Gly6Ser) variant details
- p.Gly6Ser
- gnomAD 2-113120086-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- MetaLR 0.06
- MetaSVM -0.98
- CADD 9.14
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available