G6D (p.Gly6Asp) variant of IL1RN (P18510)
G6D (p.Gly6Asp) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G6D (p.Gly6Asp) variant details
- p.Gly6Asp
- gnomAD 2-113120087-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- MetaLR 0.09
- MetaSVM -1.00
- CADD 8.58
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available
- Literature evidence available