G6A (p.Gly6Ala) variant of IL1RN (P18510)
G6A (p.Gly6Ala) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G6A (p.Gly6Ala) variant details
- p.Gly6Ala
- rs1284620319
- gnomAD 2-113120093-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- MetaLR 0.06
- MetaSVM -0.96
- CADD 9.03
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available