G58R (p.Gly58Arg) variant of IL1RN (P18510)
G58R (p.Gly58Arg) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G58R (p.Gly58Arg) variant details
- p.Gly58Arg
- ExAC rs771212516
- gnomAD rs771212516
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.39
- MetaLR 0.09
- MetaSVM -1.10
- CADD 26.90
- PolyPhen-2 0.99
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available