G29R (p.Gly29Arg) variant of IL1RN (P18510)
G29R (p.Gly29Arg) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G29R (p.Gly29Arg) variant details
- p.Gly29Arg
- gnomAD 2-113127709-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.05
- MetaLR 0.11
- MetaSVM -1.00
- CADD 8.62
- PolyPhen-2 0.01
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available