F17C (p.Phe17Cys) variant of IL1RN (P18510)
F17C (p.Phe17Cys) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
F17C (p.Phe17Cys) variant details
- p.Phe17Cys
- gnomAD 2-113127674-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.22
- CADD 17.20
- PolyPhen-2 0.82
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available