E2K (p.Glu2Lys) variant of IL1RN (P18510)
E2K (p.Glu2Lys) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
E2K (p.Glu2Lys) variant details
- p.Glu2Lys
- cosmic curated COSV52081
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.06
- CADD 14.40
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available