E22Q (p.Glu22Gln) variant of IL1RN (P18510)
E22Q (p.Glu22Gln) in IL1RN (P18510) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
E22Q (p.Glu22Gln) variant details
- p.Glu22Gln
- rs373740711
- gnomAD 2-113120128-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- MetaLR 0.08
- MetaSVM -1.01
- CADD 16.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- Literature evidence available